Purification and Identification of Novel Xanthine Oxidase Inhibitory Peptides Derived from Round Scad (<i>Decapterus maruadsi</i>) Protein Hydrolysates

Xiao Hu; Ya Zhou; Shaobo Zhou; Shengjun Chen; Yanyan Wu; Laihao Li; Xianqing Yang

doi:10.3390/md19100538

Marine Drugs (Sep 2021)

Purification and Identification of Novel Xanthine Oxidase Inhibitory Peptides Derived from Round Scad (<i>Decapterus maruadsi</i>) Protein Hydrolysates

Xiao Hu,
Ya Zhou,
Shaobo Zhou,
Shengjun Chen,
Yanyan Wu,
Laihao Li,
Xianqing Yang

Affiliations

Xiao Hu: Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China
Ya Zhou: Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China
Shaobo Zhou: School of Life Sciences, Institute of Biomedical and Environmental Science and Technology, University of Bedfordshire, Luton LU1 3JU, UK
Shengjun Chen: Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China
Yanyan Wu: Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China
Laihao Li: Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China
Xianqing Yang: Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China

DOI: https://doi.org/10.3390/md19100538
Journal volume & issue: Vol. 19, no. 10
p. 538

Abstract

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The objective of the present study was to investigate the xanthine oxidase (XO) inhibitory effects of peptides purified and identified from round scad (Decapterus maruadsi) hydrolysates (RSHs). In this study, RSHs were obtained by using three proteases (neutrase, protamex and alcalase). Among them, the RSHs of 6-h hydrolysis by neutrase displayed the strongest XO inhibitory activity and had an abundance of small peptides (914 (contained in the XO) in the XO inhibitory activity of the peptides.

Published in Marine Drugs

ISSN: 1660-3397 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: http://www.mdpi.com/journal/marinedrugs

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