The achievement and prospect of deep brain stimulation for the treatment of movement disorders

Abstract

Deep brain stimulation (DBS) was first used in the treatment of essential tremor in 1987, and later used in the treatment of advanced Parkinson's disease (PD), drug⁃refractory dystonia, other types of tremor and Tourette's syndrome, which can reduce the clinical symptoms and improve quality of life of patients for a long time, as a major progress in surgical treatment of movement disorders in past 30 years. However, there are also limitations that can not effectively improve the axial system symptoms of PD, secondary dystonia, or related side effects such as cognitive impairment and balance disorder. In recent years, the exploration of new targets and innovation of DBS equipment have further promoted the treatment of DBS for movement disorders. This article reviews relevant research to provide clinical guidance. DOI：10.3969/j.issn.1672⁃6731.2020.12.001

Keywords

• parkinson disease
• dystonia
• tremor
• tourette syndrome
• huntington disease
• deep brain stimulation
• review