Nature Communications (Sep 2021)

A CDK-regulated chromatin segregase promoting chromosome replication

  • Erika Chacin,
  • Priyanka Bansal,
  • Karl-Uwe Reusswig,
  • Luis M. Diaz-Santin,
  • Pedro Ortega,
  • Petra Vizjak,
  • Belen Gómez-González,
  • Felix Müller-Planitz,
  • Andrés Aguilera,
  • Boris Pfander,
  • Alan C. M. Cheung,
  • Christoph F. Kurat

DOI
https://doi.org/10.1038/s41467-021-25424-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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How cells coordinate chromatin dynamics with the cell cycle machinery to promote genome duplication during S phase is still a matter of study. Here the authors reveal by in vitro reconstitution assays that the AAA + -ATPase containing Yta7 protein in S. cerevisiae promotes chromatin.