Epidemiology of Influenza-like Illness and Respiratory Viral Etiology in Adult Patients in Taiyuan City, Shanxi Province, China between 2018 and 2019
Zhao Jia,
Puna Xue,
Ruihong Gao,
Rui Wang,
Lifeng Zhao,
Zhihong Zuo,
Li Gao,
Rui Han,
Hong Yao,
Jiane Guo,
Jihong Xu,
Zhen Zhu,
Jitao Wang
Affiliations
Zhao Jia
School of Public Health, Shanxi Medical University, 56 Xinjian South Road, Taiyuan 030001, China
Puna Xue
School of Public Health, Shanxi Medical University, 56 Xinjian South Road, Taiyuan 030001, China
Ruihong Gao
School of Public Health, Shanxi Medical University, 56 Xinjian South Road, Taiyuan 030001, China
Rui Wang
Taiyuan Center for Disease Control and Prevention, No. 22, Huazhang West Street, Xiaodian District, Taiyuan 030032, China
Lifeng Zhao
Taiyuan Center for Disease Control and Prevention, No. 22, Huazhang West Street, Xiaodian District, Taiyuan 030032, China
Zhihong Zuo
Taiyuan Center for Disease Control and Prevention, No. 22, Huazhang West Street, Xiaodian District, Taiyuan 030032, China
Li Gao
Taiyuan Center for Disease Control and Prevention, No. 22, Huazhang West Street, Xiaodian District, Taiyuan 030032, China
Rui Han
Taiyuan Center for Disease Control and Prevention, No. 22, Huazhang West Street, Xiaodian District, Taiyuan 030032, China
Hong Yao
School of Public Health, Shanxi Medical University, 56 Xinjian South Road, Taiyuan 030001, China
Jiane Guo
School of Public Health, Shanxi Medical University, 56 Xinjian South Road, Taiyuan 030001, China
Jihong Xu
Taiyuan Center for Disease Control and Prevention, No. 22, Huazhang West Street, Xiaodian District, Taiyuan 030032, China
Zhen Zhu
NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Jitao Wang
School of Public Health, Shanxi Medical University, 56 Xinjian South Road, Taiyuan 030001, China
To determine the epidemiological status of influenza and understand the distribution of common respiratory viruses in adult patients with influenza-like illness (ILI) cases in Taiyuan City, Shanxi Province, China, epidemiological data between 2018 and 2019 were retrieved from the China Influenza Surveillance Information System, and two sentinel ILI surveillance hospitals were selected for sample collection. All specimens were screened for influenza virus (IFV) and the other 14 common respiratory viruses using real-time polymerase chain reaction. The results of the 2-year ILI surveillance showed that 26,205 (1.37%) of the 1,907,869 outpatients and emergency patients presented with ILI, with an average annual incidence of 297.75 per 100,000 individuals, and ILI cases were predominant in children <15 years (21,348 patients, 81.47%). Of the 2713 specimens collected from adult patients with ILI, the overall detection rate of respiratory viruses was 20.13%, with IFV being the most frequently detected (11.79%) and at a relatively lower rate than other respiratory viruses. Further subtype analysis indicated an alternating or mixed prevalence of H1N1 (2009), H3N2, Victoria, and Yamagata subtypes. This study provides a baseline epidemiological characterization of ILI and highlights the need for a nationwide detection and surveillance system for multiple respiratory pathogens.
