Nature Communications (Sep 2022)
Pangenomic analysis of Chinese gastric cancer
- Yingyan Yu,
- Zhen Zhang,
- Xiaorui Dong,
- Ruixin Yang,
- Zhongqu Duan,
- Zhen Xiang,
- Jun Li,
- Guichao Li,
- Fazhe Yan,
- Hongzhang Xue,
- Du Jiao,
- Jinyuan Lu,
- Huimin Lu,
- Wenmin Zhang,
- Yangzhen Wei,
- Shiyu Fan,
- Jing Li,
- Jingya Jia,
- Jun Zhang,
- Jun Ji,
- Pixu Liu,
- Hui Lu,
- Hongyu Zhao,
- Saijuan Chen,
- Chaochun Wei,
- Hongzhuan Chen,
- Zhenggang Zhu
Affiliations
- Yingyan Yu
- Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine
- Zhen Zhang
- Department of Radiation Oncology and Department of Oncology, Shanghai Medical College, Fudan University Shanghai Cancer Center
- Xiaorui Dong
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Ruixin Yang
- Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine
- Zhongqu Duan
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Zhen Xiang
- Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine
- Jun Li
- Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine
- Guichao Li
- Department of Radiation Oncology and Department of Oncology, Shanghai Medical College, Fudan University Shanghai Cancer Center
- Fazhe Yan
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Hongzhang Xue
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Du Jiao
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Jinyuan Lu
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Huimin Lu
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Wenmin Zhang
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Yangzhen Wei
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Shiyu Fan
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Jing Li
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Jingya Jia
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Jun Zhang
- Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
- Jun Ji
- Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine
- Pixu Liu
- Institute of Cancer Stem Cell, Dalian Medical University
- Hui Lu
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Hongyu Zhao
- SJTU-Yale Joint Center for Biostatistics and Data Science, Shanghai Jiao Tong University
- Saijuan Chen
- National Facility for Translational Medicine (Shanghai), The Institute of Translational Medicine, Shanghai Jiao Tong University
- Chaochun Wei
- Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
- Hongzhuan Chen
- Shanghai Collaborative Innovation Center of Translational Medicine, Shanghai Jiao Tong University School of Medicine
- Zhenggang Zhu
- Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine
- DOI
- https://doi.org/10.1038/s41467-022-33073-7
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 13
Abstract
Human pan-genomics are increasing our knowledge of genomic diversity and genetic factors in disease. Here, the authors built a gastric cancer pan-genome that included the sequences of Chinese Han patients, and predicted putative and previously unaligned genes associated with gastric cancer.
