Cardiovascular Ultrasound (Aug 2012)

A modified regimen of extracorporeal cardiac shock wave therapy for treatment of coronary artery disease

  • Wang Yu,
  • Guo Tao,
  • Ma Tie-kun,
  • Cai Hong-yan,
  • Tao Si-ming,
  • Peng Yun-zhu,
  • Yang Ping,
  • Chen Ming-qing,
  • Gu Yun

DOI
https://doi.org/10.1186/1476-7120-10-35
Journal volume & issue
Vol. 10, no. 1
p. 35

Abstract

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Abstract Background Cardiac shock wave therapy (CSWT) improves cardiac function in patients with severe coronary artery disease (CAD). We aimed to evaluate the clinical outcomes of a new CSWT treatment regimen. Methods The 55 patients with severe CAD were randomly divided into 3 treatment groups. The control group (n = 14) received only medical therapy. In group A ( n = 20), CSWT was performed 3 times within 3 months. In group B ( n = 21), patients underwent 3 CSWT sessions/week, and 9 treatment sessions were completed within 1 month. Primary outcome measurement was 6-minute walk test (6MWT). Other measurements were also evaluated. Results The 6MWT, CCS grading of angina, dosage of nitroglycerin, NYHA classification, and SAQ scores were improved in group A and B compared to control group. Conclusions A CSWT protocol with 1 month treatment duration showed similar therapeutic efficacy compared to a protocol of 3 months duration. Clinical trial registry We have registered on ClinicalTrials.gov, the protocol ID is CSWT IN CHINA.

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