Study of Local Irritant Action of a Prototype Drug Based on Esters of Fatty Acids

Abstract

In this article, we have presented studies of the local irritating effect of a prototype wound-healing preparation based on water-based fatty acid esters with allantoin. The study of local irritant action included use of extreme dilutions of the drug for intradermal and local use in the induction and provocative phases. The assessment was carried out in points, in the experimental group it was on average 1 point, in control animals on average it was also equal to 1. These studies indicate that the composition has a mild skin reaction of sensitized guinea pigs and does not cause an allergic reaction.