Гинекология (Oct 2014)

Women with hypoplastic endomentrium: getting ready for pregnancy

  • S Yu Kalinchenko,
  • M I Zhilenko,
  • D A Gusakova,
  • A V Dymova

Journal volume & issue
Vol. 16, no. 5
pp. 62 – 66

Abstract

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Different pathological conditions (endocrinopathies, infectious agents prior to repeated intrauterine manipulations, the presence of functionally defective receptors endometrial tissue to the corresponding steroid hormones, progesterone autosensibilization) can lead to the further development of endometrial insolvency. Hypoplasia of the endometrium may be a consequence of both systemic problems (hormone deficiency, decreased blood flow in the branches of the uterine arteries, hypercoagulability) and local disturbances in the endometrium (the receptor, immunological changes, with a predominance of the increased activity of natural killer cells, suppression of immunosuppressive mechanisms, and decreased activity of macrophages). The article describes the methods of diagnosis and treatment of the basic principles of hypoplasia of the endometrium.

Keywords