Impact of gibberellin-regulated protein allergy on quality of life

Abstract

The purpose of this study was to investigate possible allergens that cause gibberellin-regulated protein allergy. For this purpose, a thorough search of relevant information in the databases Embase, PubMed, Scopus, and Web of Science, presented for 2018-2023, was carried out. The study showed that about 4% of the world’s population suffers from food allergies. The main manifestations of allergic reactions and the degree of resistance to allergens depend on the age group of patients. The study identified the following food allergens in gibberellin-regulated protein allergy: Pru p7 (peach), Pru m7 (Japanese apricot), Cit s7 (orange), Pun g7 (pomegranate), Pru av7 (sweet cherry), Cap a7 (bell pepper), Fra a3 (strawberry), Cup s7 (cypress pollen). Gibberellin-regulated protein allergy is characterised by a predominantly adolescent and young adult population. The symptoms of this allergy usually manifest themselves in the form of oral syndrome, facial swelling (including eyelids), anaphylactic reactions and are aggravated by the action of cofactors. Such manifestations substantially impair the quality of life of patients, causing a social, psychological, and economic burden.

Keywords

• Immune response
• cross-reaction
• hypersensitivity
• food
• pollen