FORMULASI TABLET SERBUK PISANG RAJA (Musa xparadisiaca AAB) SEBAGAI PENUTUP TUKAK LAMBUNG PADA TIKUS

Abstract

Mucoadhesive is a topic of current interest in the design of drug delivery system and treatment of peptic ulcers. This concept is based on the strength of adhesion of a protective material to the mucosa. King Banana (Musa xparadisiaca AAB) is often used in the treatment of abdominal pain. It has been suspected having muchoadhesive strength to cover peptic ulcer. The study was armed to formulate king banana tablet which has muchoadhesive ability to protect gastric mucosa become ulcer. The aim of peptic ulcer cover test was to see the ability of king banana tablet to covered ulcer at the groups test that received different treatment of the negative control group (solvent), the banana tablet suspension group, and sucralfate group. The ulcer severity was determined by scoring method. All experimental data were tested by SPSS analytical statistics. The result showed that king banana tablet has similar strength to peptic ulcer cover of sucralfat and not significantly different.

Keywords

• king banana tablet
• peptic ulcers