Nature Communications (Mar 2018)

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

  • Jutaek Nam,
  • Sejin Son,
  • Lukasz J. Ochyl,
  • Rui Kuai,
  • Anna Schwendeman,
  • James J. Moon

DOI
https://doi.org/10.1038/s41467-018-03473-9
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

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Photothermal therapy (PTT) for cancer treatment is currently limited to local, accessible, tumors. Here the authors show that PTT combination with chemotherapy, by stimulating an immune response, is effective against distant tumors and establishes immune memory, thus providing a strategy to target metastatic disease.