Chitosan-Based Hydrogel in the Management of Dermal Infections: A Review
Popat Mohite,
Pudji Rahayu,
Shubham Munde,
Nitin Ade,
Vijay R. Chidrawar,
Sudarshan Singh,
Titilope J. Jayeoye,
Bhupendra G. Prajapati,
Sankha Bhattacharya,
Ravish J. Patel
Affiliations
Popat Mohite
Department of Pharmaceutical Quality Assurance, A.E.T.’s St. John Institute of Pharmacy and Research, Palghar 401404, Maharashtra, India
Pudji Rahayu
Department of Pharmacy of Tanjung Karang State Health Polytechnic, Soekarno-Hatta, Bandar Lampung 35145, Lampung, Indonesia
Shubham Munde
Department of Pharmaceutical Quality Assurance, A.E.T.’s St. John Institute of Pharmacy and Research, Palghar 401404, Maharashtra, India
Nitin Ade
Department of Pharmaceutical Quality Assurance, A.E.T.’s St. John Institute of Pharmacy and Research, Palghar 401404, Maharashtra, India
Vijay R. Chidrawar
SVKM’s NMIMS School of Pharmacy and Technology Management, Jadcharla 509301, Telangana, India
Sudarshan Singh
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand
Titilope J. Jayeoye
Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand
Bhupendra G. Prajapati
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Mehsana 384012, Gujarat, India
Sankha Bhattacharya
Department of Pharmaceutics, School of Pharmacy and Technology Management, SVKM’s NMIMS Deemed-to-be-University, Shirpur 425405, Maharashtra, India
Ravish J. Patel
Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Anand 388421, Gujarat, India
The main objective of this review is to provide a comprehensive overview of the current evidence regarding the use of chitosan-based hydrogels to manage skin infections. Chitosan, a naturally occurring polysaccharide derived from chitin, possesses inherent antimicrobial properties, making it a promising candidate for treating various dermal infections. This review follows a systematic approach to analyze relevant studies that have investigated the effectiveness of chitosan-based hydrogels in the context of dermal infections. By examining the available evidence, this review aims to evaluate these hydrogels’ overall efficacy, safety, and potential applications for managing dermal infections. This review’s primary focus is to gather and analyze data from different recent studies about chitosan-based hydrogels combating dermal infections; this includes assessing their ability to inhibit the growth of microorganisms and reduce infection-related symptoms. Furthermore, this review also considers the safety profile of chitosan-based hydrogels, examining any potential adverse effects associated with their use. This evaluation is crucial to ensure that these hydrogels can be safely utilized in the management of dermal infections without causing harm to patients. The review aims to provide healthcare professionals and researchers with a comprehensive understanding of the current evidence regarding the use of chitosan-based hydrogels for dermal infection management. The findings from this review can contribute to informed decision-making and the development of potential treatment strategies in this field.
