Nature Communications (Jun 2019)

Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex

  • Ulf Knoblich,
  • Lawrence Huang,
  • Hongkui Zeng,
  • Lu Li

DOI
https://doi.org/10.1038/s41467-019-10498-1
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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Synchronised neuronal activity is essential for cortical function, yet mechanistic insights into this process remain limited. Here, authors use a combination of in vivo imaging and targeted whole-cell recordings to demonstrate that Somatostatin neurons, in the superficial layers of the mouse primary visual cortex, exhibit functional heterogeneity and can be classified into two distinct subtypes characterized as either having type I uncorrelated, or type II highly correlated with network activity.