Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development

Abstract

Outer radial glial cells (oRGs) are undifferentiated cells that divide in the subventricular zone during neurodevelopment, but the underlying mechanisms are not fully understood. Here the authors show that Lzts1 positively controls both neuronal delamination and generation of oRG-like cell types.