A human ex vivo coculture model to investigate peritoneal metastasis and innovative treatment options

Abstract

Peritoneal metastasis (PM) is commonly observed in patients with colorectal cancer (CRC). The outcome of these patients is poor, with an average survival of only six months without therapy, which requires a better understanding of PM biology and new treatment strategies.

Keywords

• colorectal cancer
• ex vivo model
• hipec
• peritoneal metastasis
• peritoneum