Journal of International Medical Research (Aug 2021)

Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis

  • Junfeng Han,
  • Long Yuan,
  • Jianguo Li,
  • Chunbao Liang,
  • Dong Zhang,
  • Zaoxian Mei

DOI
https://doi.org/10.1177/03000605211035889
Journal volume & issue
Vol. 49

Abstract

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Objective To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis. Methods One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as the observation group, and 130 patients with cavitary tuberculosis who underwent treatment with drugs only were selected as the control group. Changes in cavity size and sputum tests were compared between the two groups. In addition, adverse reactions were monitored. Results The number of cases with cavity closure was significantly higher in the observation group than in the control group at different time points. The number and proportion of negative sputum samples in the observation group were significantly higher than those in the control group. The treatment success rate was 98.46% in the observation group and 92.3% in the control group. No recurrence was observed in the observation group, and 8.3% of cases in the control group showed recurrence. Conclusions TTCP for the treatment of cavity tuberculosis showed good outcomes, with limited side effects and minimal complications.