Cutting-edge microneedle innovations: Transforming the landscape of cardiovascular and metabolic disease management
Xiaoning Zhang,
Ming Li,
Qiang Gao,
Xiaoya Kang,
Jingyao Sun,
Yao Huang,
Hong Xu,
Jing Xu,
Songren Shu,
Jian Zhuang,
Yuan Huang
Affiliations
Xiaoning Zhang
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Ming Li
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Qiang Gao
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Xiaoya Kang
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Jingyao Sun
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Yao Huang
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Hong Xu
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Jing Xu
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China; Corresponding author
Songren Shu
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China; Corresponding author
Jian Zhuang
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China; Corresponding author
Yuan Huang
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China; Corresponding author
Summary: Cardiovascular diseases (CVDs) and metabolic disorders (MDs) have surfaced as formidable challenges to global health, significantly imperiling human well-being. Recently, microneedles (MNs) have garnered substantial interest within the realms of CVD and MD research. Offering a departure from conventional diagnostic and therapeutic methodologies, MNs present a non-invasive, safe, and user-friendly modality for both monitoring and treatment, thereby marking substantial strides and attaining pivotal achievements in this avant-garde domain, while also unfurling promising avenues for future inquiry. This thorough review encapsulates the latest developments in employing MNs for both the surveillance and management of CVDs and MDs. Initially, it succinctly outlines the foundational principles and approaches of MNs in disease surveillance and therapy. Subsequently, it delves into the pioneering utilizations of MNs in the surveillance and management of CVDs and MDs. Ultimately, this discourse synthesizes and concludes the primary findings of this investigation, additionally prognosticating on the trajectory of MN technology.
