New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides
Gilles Hanquet,
Xavier Salom-Roig,
Steve Lanners
Affiliations
Gilles Hanquet
Université de Strasbourg UMR CNRS 7509, ECPM 25 rue Becquerel, 67087 Strasbourg, France;, Email: [email protected]
Xavier Salom-Roig
Institut de Biomolécules Max Mousseron (IBMM) UMR 5247, CNRS-Université de Montpellier Place Eugène Bataillon, 34095 Montpellier, France;, Email: [email protected]
Steve Lanners
University of Namur Department of Chemistry and Namur Medicine & Drug Innovation Center (NAMEDIC) 61 rue de Bruxelles, 5000 Namur, Belgium;, Email: [email protected]
After a brief account of the biological properties of pamamycins, this review highlights the latest developments on the total synthesis and the biosynthesis of these macrodiolides.