Two New Phenolic Compounds from the Heartwood of Caesalpinia sappan L.
Ming-Bo Zhao,
Jun Li,
She-Po Shi,
Chen-Qiu Cai,
Peng-Fei Tu,
Li Tang,
Ke-Wu Zeng,
Yong Jiang
Affiliations
Ming-Bo Zhao
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
Jun Li
Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
She-Po Shi
Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
Chen-Qiu Cai
College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China
Peng-Fei Tu
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
Li Tang
College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China
Ke-Wu Zeng
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
Yong Jiang
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
Two new phenolic compounds, epicaesalpin J and 7,10,11-trihydroxydracaenone, were isolated from the heartwood of Caesalpinia sappan L. Their structures were identified by spectroscopic analysis methods, such as 1D and 2D NMR, along with the high resolution mass spectral data. The NO inhibition activities of two new compounds and six known compounds were tested.
