Chemical Components and Pharmacological Activities of Terpene Natural Products from the Genus Paeonia
Dan-Dan Zhao,
Li-Li Jiang,
Hong-Yi Li,
Peng-Fei Yan,
Yan-Long Zhang
Affiliations
Dan-Dan Zhao
Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education, School of Chemistry and Materials Science, Heilongjiang University, 74 Xue-Fu Road, Nan-Gang District, Harbin 150080, China
Li-Li Jiang
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Sciences, Heilongjiang University, Harbin 150080, China
Hong-Yi Li
Heilongjiang University Hospital, Harbin 150080, China
Peng-Fei Yan
Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education, School of Chemistry and Materials Science, Heilongjiang University, 74 Xue-Fu Road, Nan-Gang District, Harbin 150080, China
Yan-Long Zhang
Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Sciences, Heilongjiang University, Harbin 150080, China
Paeonia is the single genus of ca. 33 known species in the family Paeoniaceae, found in Asia, Europe and Western North America. Up to now, more than 180 compounds have been isolated from nine species of the genus Paeonia, including terpenes, phenols, flavonoids, essential oil and tannins. Terpenes, the most abundant naturally occurring compounds, which accounted for about 57% and occurred in almost every species, are responsible for the observed in vivo and in vitro biological activities. This paper aims to give a comprehensive overview of the recent phytochemical and pharmacological knowledge of the terpenes from Paeonia plants, and enlighten further drug discovery research.
