Cardiovascular Diabetology (Aug 2017)

Admission blood glucose and 10-year mortality among patients with or without pre-existing diabetes mellitus hospitalized with heart failure

  • Osnat Itzhaki Ben Zadok,
  • Ran Kornowski,
  • Ilan Goldenberg,
  • Robert Klempfner,
  • Yoel Toledano,
  • Yitschak Biton,
  • Enrique Z. Fisman,
  • Alexander Tenenbaum,
  • Gregory Golovchiner,
  • Ehud Kadmon,
  • Alexander Omelchenko,
  • Tuvia Ben Gal,
  • Alon Barsheshet

DOI
https://doi.org/10.1186/s12933-017-0582-y
Journal volume & issue
Vol. 16, no. 1
pp. 1 – 9

Abstract

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Abstract Background High admission blood glucose (ABG) level has been associated with a poor short-term outcome among non-diabetic patients with heart failure (HF). We aimed to investigate the association between ABG levels and long-term (10 years) mortality in patients with or without pre-existing diabetes mellitus (DM) admitted with HF. Methods We analyzed data on 1811 patients with DM and 2182 patients without pre-existing DM who were hospitalized with HF during a prospective national survey. The relationship between ABG and 10-year mortality was assessed using the Cox proportional hazard model adjusting for multiple variables. ABG was analyzed both as a categorical (200 mg/dL) and as a continuous variable. Results At 10 years of follow-up the cumulative probability of mortality was 85 and 78% among patients with DM and patients with no pre-existing DM (p 200 mg/dL had an increased mortality risk (>200 mg/dL versus 200 mg/dL is associated with increased mortality risk.

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