Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans

Abstract

Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors. They analyse and compare the glycan occupancy on membrane and secreted glycoproteins, which is helpful to reveal the relationship between neutrophil glycoproteins and their function.