Infection and Drug Resistance (May 2023)
Spontaneous Prostatic Hemorrhage in a COVID-19 Patient: A Case Report
Abstract
Jiaguo Huang,1,* Hongxiang Ding,1,* Chao Feng,2 Dikai Mao,1 Shengcheng Tai1 1Department of Urology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, People’s Republic of China; 2School of Medicine, Hangzhou Normal University, Hangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shengcheng Tai, Department of Urology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, No. 728 North Yucai Road, Xiaoshan District, Hangzhou, People’s Republic of China, Tel +8613516811191, Email [email protected]: Hematuria occurring in patients with acute kidney injury caused by Corona Virus Disease 2019 (COVID-19) infection has been reported. However, cases of macroscopic hematuria in COVID-19 patients leading to a severe decrease in hemoglobin have not been reported heretofore. Herein, we describe the case of a 56-year-old male patient who suffered from spontaneous prostatic hemorrhage caused by thrombocytopenia and coagulation dysfunction associated with COVID-19 infection, which manifested as macroscopic hematuria, bladder blood clot tamponade and severe hemoglobin decline. Prostatic hemorrhage was diagnosed by endoscopy. There was no recurrence of macroscopic hematuria after undergoing transurethral prostate electrocoagulation for hemostasis, infusing plasma to supplement coagulation factors and taking finasteride. One month after the bleeding event, the patient’s blood routine reexamination revealed that the platelet count returned to the normal value and coagulation was normal.Keywords: COVID-19, hematuria, prostatic hemorrhage, thrombocytopenia, coagulation dysfunction, bleeding event