PLoS Pathogens (Aug 2020)

African swine fever whole-genome sequencing-Quantity wanted but quality needed.

  • Jan H Forth,
  • Leonie F Forth,
  • Sandra Blome,
  • Dirk Höper,
  • Martin Beer

DOI
https://doi.org/10.1371/journal.ppat.1008779
Journal volume & issue
Vol. 16, no. 8
p. e1008779

Abstract

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The pandemic spread of African swine fever virus (ASFV) genotype II (GTII) has led to a global crisis. Since the circulating strains are almost identical, time and money have been mis-invested in whole-genome sequencing the last years. New methods, harmonised protocols for sample selection, sequencing, and bioinformatics are therefore urgently needed.