502 The epigenetics of the now known 330 lupus genetic risk loci in two ancestries are independently consonant with causal regulatory mechanisms involving epstein-barr virus (EBV)-encoded transcription co-factors expressed in EBV-infected, EBV latency III-expressing B cells (LCLs)

• John B Harley,
• Viktoryia Laurynenka,
• Sreeja Parameswaran,
• Xiaoting Chen,
• Leah C Kottyan,
• Matthew T Weirauch,
• Kenneth M Kaufman,
• Iouri Chepelev

Affiliations

John B Harley

1US Department of Veterans Affairs Medical Center, Cincinnati, Ohio, USA

Viktoryia Laurynenka

1US Department of Veterans Affairs Medical Center, Cincinnati, Ohio, USA

Sreeja Parameswaran

17 Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

Xiaoting Chen

2 Center for Autoimmune Genomics and Etiology, Cincinnati Children`s Hospital Medical Center, Cincinnati, Ohio, USA

Leah C Kottyan

3Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

Matthew T Weirauch

2 Center for Autoimmune Genomics and Etiology, Cincinnati Children`s Hospital Medical Center, Cincinnati, Ohio, USA

Kenneth M Kaufman

7Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

Iouri Chepelev

1N/A, Cincinnati Education and Research Foundation for Veterans, USA