Southern African Journal of Infectious Diseases (Oct 2020)
South African Society of Clinical Microbiology Clostridioides difficile infection diagnosis, management and infection prevention and control guideline
- Trusha Nana,
- Chanelle Moore,
- Tom Boyles,
- Adrian J. Brink,
- Joy Cleghorn,
- Lesley M. Devenish,
- Briette du Toit,
- Ernst S. Fredericks,
- Molebogeng R. Lekalakala-Mokaba,
- Caroline Maluleka,
- Muhammad N. Rajabally,
- Gary Reubenson,
- Liliwe Shuping,
- Karin Swart,
- Khine Swe Swe Han,
- Jeannette Wadula,
- Justyna Wojno,
- Warren Lowman
Affiliations
- Trusha Nana
- Department of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and Charlotte Maxeke Johannesburg Academic Hospital Microbiology Laboratory, National Health Laboratory Services, Johannesburg,
- Chanelle Moore
- Ampath Laboratories, Johannesburg
- Tom Boyles
- Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London
- Adrian J. Brink
- Department of Medical Microbiology, Faculty of Health Sciences, University of Cape Town, Cape Town
- Joy Cleghorn
- Life Healthcare Group, Johannesburg
- Lesley M. Devenish
- Department of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and Infection Control Services Laboratory, National Health Laboratory Services, Johannesburg
- Briette du Toit
- Mediclinic Southern Africa, Cape Town
- Ernst S. Fredericks
- Department of Physiology, Faculty of Science, Nelson Mandela University, Port Elizabeth
- Molebogeng R. Lekalakala-Mokaba
- Department of Microbiology, Faculty of Health Sciences, Sefako Makgatho Health Sciences University, Pretoria, South Africa; and Dr George Mukhari Academic Hospital Microbiology Laboratory, National Health Laboratory Services, Pretoria,
- Caroline Maluleka
- Department of Microbiology, Faculty of Health Sciences, Sefako Makgatho Health Sciences University, Pretoria, South Africa; and Dr George Mukhari Academic Hospital Microbiology Laboratory, National Health Laboratory Services, Pretoria,
- Muhammad N. Rajabally
- Mediclinic Constantiaberg, Cape Town
- Gary Reubenson
- Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
- Liliwe Shuping
- Centre for Healthcare-Associated Infections, National Institute for Communicable Diseases, a division of National Health Laboratory Service, Johannesburg
- Karin Swart
- Netcare Hospitals Limited, Johannesburg
- Khine Swe Swe Han
- Medical Microbiology Department, Inkosi Albert Luthuli Central Hospital Academic Complex, National Health Laboratory Services, Durban, South Africa; and Department of Medical Microbiology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban
- Jeannette Wadula
- Department of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and Chris Hani Baragwanath Hospital Microbiology Laboratory, National Health Laboratory Services, Johannesburg,
- Justyna Wojno
- Lancet Laboratories, Cape Town
- Warren Lowman
- Department of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Clinical Microbiology, PathCare/Vermaak Pathologists, Johannesburg, South Africa; and Department of Clinical Microbiology and Infection Prevention and Control, WITS Donald Gordon Medical Centre, Johannesburg
- DOI
- https://doi.org/10.4102/sajid.v35i1.219
- Journal volume & issue
-
Vol. 35,
no. 1
pp. e1 – e26
Abstract
Clostridioides difficile infection (CDI) is a problem in both developed and developing countries and is a common hospital-acquired infection. This guideline provides evidence-based practical recommendations for South Africa and other developing countries. The scope of the guideline includes CDI diagnostic approaches; adult, paediatric and special populations treatment options; and surveillance and infection prevention and control recommendations.
Keywords
- clostridioides difficile
- diagnosis
- treatment
- surveillance
- infection control
- infection prevention
- outbreak.
