Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis

Abstract

The purpose of this investigation is to study antioxidant activity of sterically hindered phenol — thiophane in rats with toxical hepatitis. Increase of diene and triene conjugates as well as fluorescent products in hepar tissue was revealed. Course intragastric administration of thiophane decreased significantly the content of lipid peroxidation products (diene and triene conjugates, fluorescent products) and held over the α-tocopherol content in hepar tissue.

Keywords

• тиофан
• перекисное окисление липидов
• гепатопротектор
• токсический гепатит