Do androgen levels play a role in predicting complications of preeclampsia?

Abstract

Preeclampsia is a multisystem disorder characterized by new-onset hypertension and proteinuria after 20 weeks of gestation. The association between androgens and hypertension has been demonstrated. The purpose of this study was to determine the relationship between androgen levels and fetal and maternal complications in patients with preeclampsia. This study included 178 patients who were followed up with the diagnosis of preeclampsia and gave birth in High-Risk Pregnancy Clinic of Zekai Tahir Burak Women’s Health Research and Education Hospital. Androstenedione, dehydroepiandrosterone sulfate, total testosterone and free testosterone levels were measured by the Immulite 200 chemiluminescence method on the BioDPC Isodata 100 Series Gamma Counter in venous blood samples. Maternal complications and fetal complications were recorded. The relationship between these complications and androgen levels was examined. Free testosterone levels were significantly higher in those with a 1-min Apgar score [Med-Science 2019; 8(4.000): 875-80]

Keywords

• preeclampsia
• androgens
• maternal complications
• fetal complications