Veterinary Medicine and Science (Jul 2022)

Spinal epidural and synovial lipomatosis in a 3‐year‐old Eurasian dog receiving sustained steroid therapy

  • Marion Signoret,
  • Lucile Gros,
  • Renaud Dumont,
  • Claire Dally,
  • Kevin Le Boedec,
  • Laurent Cauzinille

DOI
https://doi.org/10.1002/vms3.842
Journal volume & issue
Vol. 8, no. 4
pp. 1373 – 1377

Abstract

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Abstract This report describes a spinal cord epidural and synovial lipomatosis in a 3‐year‐old neutered male Eurasian dog. This dog presented for ambulatory paraparesis and was previously treated with immunosuppressive dosages of prednisolone for 2 years. Computed tomography (CT) myelography and magnetic resonnance imaging (MRI) images identified dorsal compression of the thoraco‐lumbar spinal cord by hypertrophic epidural fat. Histological examination identified extensive well‐differentiated mature adipose tissue in the subepithelial area of the tarsal synovium. Prednisolone is a reported predisposing factor in humans with lipomatosis.

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