Association of sleep quality and sleep duration with serum uric acid levels in adults.

Abstract

ObjectiveTo date, the association between sleep duration or sleep quality and hyperuricemia has remained unclear. In addition, sleep duration and quality were not considered concomitantly in previous studies. Thus, this study was aimed toward an examination of the association of sleep duration and quality with uric acid level in a Taiwanese population.MethodsA total of 4,555 patients aged ≥18 years were enrolled in this study. The sleep duration was classified into three groups: short (5.ResultsPoor sleepers were younger and had lower body mass index, blood pressure, uric acid, blood sugar, cholesterol, creatinine level, shorter sleep duration, and engaged in less exercise but had a higher white blood cell count and prevalence of smoking as compared to good sleepers. There were also differences in body mass index, blood pressure, uric acid, blood sugar, lipid profiles, and sleep quality among subjects with different sleep durations. After adjusting for other variables, poor sleep quality was associated with lower uric acid levels. In addition, short sleep duration was positively associated with higher uric acid levels.ConclusionsPoor sleep quality was related to lower uric acid levels, whereas short sleep duration was associated with higher uric acid levels.