Patients with HIV-associated cancers have evidence of increased T cell dysfunction and exhaustion prior to cancer diagnosis

• Anuradha Ganesan,
• Xun Wang,
• Yanhong Deng,
• Kurt A Schalper,
• Ryan C Maves,
• Brian Agan,
• Brinda Emu,
• Jason Okulicz,
• Omkar Chaudhary,
• Diane Trotta,
• Kaicheng Wang,
• Xiuping Chu,
• Chip Bradley,
• Karl Kronmann,
• Christina M Schofield,
• Jason M Blaylock,
• Susan M Kaech

Affiliations

Anuradha Ganesan

2 Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Infectious Disease Clinical Research Program, Bethesda, Maryland, USA

Xun Wang

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic CenterSun, Yat-sen University, Guangzhou, China

Yanhong Deng

Yale Center for Analytical Sciences, Yale University School of Medicine, New Haven, Connecticut, USA

Kurt A Schalper

Pathology, Yale School of Medicine, New Haven, Connecticut, USA

Ryan C Maves

Division of Infectious Diseases, Naval Medical Center San Diego, San Diego, California, USA

Brian Agan

2 Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Infectious Disease Clinical Research Program, Bethesda, Maryland, USA

Brinda Emu

Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA

Jason Okulicz

4Infectious Disease Service, San Antonio Military Medical Centre, USA

Omkar Chaudhary

Internal Medicine; Infectious Disease, Yale University School of Medicine, New Haven, Connecticut, USA

Diane Trotta

Flow Cytometry Facility, Yale University School of Medicine, New Haven, Connecticut, USA

Kaicheng Wang

School of Public Health, Yale University, New Haven, Connecticut, USA

Xiuping Chu

Infectious Disease Clinical Research Program, Bethesda, Maryland, USA

Chip Bradley

Infectious Disease Clinical Research Program, Bethesda, Maryland, USA

Karl Kronmann

Internal Medicine, Naval Medical Center Portsmouth, Portsmouth, Virginia, USA

Christina M Schofield

Internal Medicine; Infectious Diseases, Madigan Army Medical Center, Tacoma, Washington, USA

Jason M Blaylock

Internal Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA

Susan M Kaech

Departments of Immunobiology, Salk Institute, La Jolla, California, USA