Clinical Medicine Insights: Oncology (Jul 2021)

Primary Pleural Squamous Cell Carcinoma, Highly Positive PD-L1, Shows Marked Response to Camrelizumab: A Case Report

  • Yao Wang,
  • Ying Gao,
  • Hai-Ruo Chen,
  • Hong Liu,
  • Xi Fu,
  • Ran Yan,
  • Feng-Ming You,
  • Zhuo-Hong Li

DOI
https://doi.org/10.1177/11795549211028571
Journal volume & issue
Vol. 15

Abstract

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Here, we reported the rare case of primary pleural squamous cell carcinoma (PPSCC) in a 71-year-old male patient. After chemo and targeted therapies, the patient showed continuous tumor progression and clinical deterioration. Fortunately, the patient had a high expression level of PD-L1 (80%) in the tumor tissues. Ultimately, the patient survived for additional 6 months with camrelizumab treatment. In summary, camrelizumab may be a good candidate for the treatment of PPSCC, especially in tumors with high PD-L1 expression.