Mediterranean Journal of Hematology and Infectious Diseases (Feb 2014)

EARLY AND LATE COMPLICATIONS RELATED TO CENTRAL VENOUS CATHETERS IN HAEMATOLOGICAL MALIGNANCIES: A RETROSPECTIVE ANALYSIS OF 1102 PATIENTS

  • Salvatore Giacomo Morano,
  • Lorenzo Coppola,
  • Roberto Latagliata,
  • Paola Berneschi,
  • Antonio Chistolini,
  • Alessandra Micozzi,
  • Corrado Girmenia,
  • Massimo Breccia,
  • Gregorio Brunetti,
  • Angela Matturro,
  • Giovanni Rosa,
  • Pietro Guerrisi,
  • Franco Mandelli,
  • Roberto Foà,
  • Giuliana Alimena

DOI
https://doi.org/10.4084/mjhid.2014.011
Journal volume & issue
Vol. 6, no. 1
pp. e2014011 – e2014011

Abstract

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Several severe complications may be associated with the use of central venous catheters (CVC). We retrospectively evaluated on a large cohort of patients the incidence of CVC-related early and late complications. From 7/99 to 12/2005, 1102 CVC have been implanted at our Institution in 881 patients with haematological malignancies (142,202 total day number of implanted CVC). Early mechanic complications were 79 (7.2% - 0.55/1,000 days/CVC). Thirty-nine episodes of early infective complications (<1 week from CVC implant) occurred (3.5% - 0.3/1000 days/CVC): furthermore, 187 episodes of CVC-related sepsis (17% - 1.3/1000 days/CVC) were recorded. There were 29 episodes (2.6%) of symptomatic CVC-related thrombotic complications, with a median interval from CVC implant of 60 days (range 7 – 395). The rate of CVC withdrawal due to CVC-related complications was 26%. The incidence of CVC-related complications in our series is in the range reported in the literature, notwithstanding cytopenia often coexisting in haematological patients.

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