Adult T-cell leukemia/lymphoma complicated by Pneumocystis pneumonia in a non-endemic area

Mayu Kunimoto; Minoru Inomata; Haruka Chin; Yu Ito; Kazushi Fujimoto; Yutaka Muto; Moe Nomura; Kota Sato; Keita Sakamoto; Nobuyasu Awano; Naoyuki Kuse; Toshio Kumasaka; Tamiko Takemura; Takehiro Izumo

Respiratory Medicine Case Reports (Jan 2023)

Adult T-cell leukemia/lymphoma complicated by Pneumocystis pneumonia in a non-endemic area

Mayu Kunimoto,
Minoru Inomata,
Haruka Chin,
Yu Ito,
Kazushi Fujimoto,
Yutaka Muto,
Moe Nomura,
Kota Sato,
Keita Sakamoto,
Nobuyasu Awano,
Naoyuki Kuse,
Toshio Kumasaka,
Tamiko Takemura,
Takehiro Izumo

Affiliations

Mayu Kunimoto: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Minoru Inomata: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan; Corresponding author. Department of Respiratory Medicine, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan.
Haruka Chin: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Yu Ito: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Kazushi Fujimoto: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Yutaka Muto: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Moe Nomura: Department of Hematology, Japanese Red Cross Medical Center, Japan
Kota Sato: Department of Hematology, Japanese Red Cross Medical Center, Japan
Keita Sakamoto: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Nobuyasu Awano: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Naoyuki Kuse: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Toshio Kumasaka: Department of Pathology, Japanese Red Cross Medical Center, Japan
Tamiko Takemura: Department of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan
Takehiro Izumo: Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan

Journal volume & issue: Vol. 42
p. 101807

Abstract

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Adult T-cell leukemia/lymphoma (ATLL) is a human T-cell leukemia virus type 1-inducing unevenly-distributed T-cell malignancy, which is often complicated by opportunistic infections. Here, we discuss the case of a 75-year-old woman presenting with Pneumocystis pneumonia (PCP) who was subsequently diagnosed with ATLL in Tokyo, a non-endemic area of ATLL. In addition to the elevated soluble interleukin-2 receptor and the detection of flower cells in the screening blood test, the high-resolution computed tomography findings, atypical of PCP, were clues to the diagnosis of ATLL. ATLL should be considered as an underlying disease when patients present with PCP, even in non-endemic areas.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: http://www.journals.elsevier.com/respiratory-medicine-case-reports/

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