Efficacy of apheresis and concentrated platelets under different transfusion strategies

Abstract

Objective To retrospectively analyze the clinical effects of apheresis and concentrated platelets under different transfusion strategies, so as to explore more scientific transfusion strategies. Methods A total of 279 patients with thrombocytopenia, admitted to our hospital during January 2020 and October 2021, were collected.They was divided into group A(apheresis platelet transfusion alone), group B(concentrated platelet transfusion alone), and group C(both apheresis and concentrated platelet transfusion). Platelet count of three groups were measured 24 hours before and after transfusion and their CCI values were calculated and compared to understand the differences in transfusion efficiency and adverse reactions, as well as the efficacy among three groups with different blood groups. Results Patients, received solo apheresis platelets, demonstrated a lower incidence of transfusion refractoriness and adverse reactions, but also a lower treatment efficacy(14.63±13.48)(P<0.05). However, the treatment efficacy of patients, received solo concentrated apheresis, could reach 16.00±21.77, but presented a higher incidence of transfusion refractoriness and adverse reactions. Patients, received both apheresis and concentrated platelets, maintained a good treatment efficacy(16.21±16.33), with a low incidence of transfusion refractoriness and adverse reactions.At the same time, different blood types also affect the treatment efficacy of platelet transfusion. Conclusion The simultaneous transfusion of apheresis and concentrated platelets contributes to the effective treatment of patients and lower incidence of adverse reactions.

Keywords

• plabbocytopenia
• apheresis platelets
• concentrated platelets
• cci