Differential regulation of the release of tumor necrosis factor-α and of eicosanoids by mast cells in rat airways after antigen challenge

Aryene Goes Trezena; Zilma Lucia da Silva; Ricardo Martins Oliveira-filho; Amilcar Sabino Damazo; Anita Hilda Straus; Helio Kiyoshi Takahashi; Sonia Maria Oliani; Wothan Tavares de Lima

doi:10.1080/09629350310001599684

Mediators of Inflammation (Jan 2003)

Differential regulation of the release of tumor necrosis factor-α and of eicosanoids by mast cells in rat airways after antigen challenge

Aryene Goes Trezena,
Zilma Lucia da Silva,
Ricardo Martins Oliveira-filho,
Amilcar Sabino Damazo,
Anita Hilda Straus,
Helio Kiyoshi Takahashi,
Sonia Maria Oliani,
Wothan Tavares de Lima

Affiliations

Aryene Goes Trezena: Laboratory of Immunogenetics and Laboratory of Anaerobic Vaccines, Butantan Institute, São Paulo, Brazil
Zilma Lucia da Silva: Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
Ricardo Martins Oliveira-filho: Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
Amilcar Sabino Damazo: Department of Biology IBILCE, São José Rio Preto, São Paulo, Brazil
Anita Hilda Straus: Department of Biochemistry, UNIFESP, Sao Paulo, Brazil
Helio Kiyoshi Takahashi: Department of Biochemistry, UNIFESP, Sao Paulo, Brazil
Sonia Maria Oliani: Department of Biology IBILCE, São José Rio Preto, São Paulo, Brazil
Wothan Tavares de Lima: Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

DOI: https://doi.org/10.1080/09629350310001599684
Journal volume & issue: Vol. 12, no. 4
pp. 237 – 246

Abstract

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Background: Rat trachea display a differential topographical distribution of connective tissue mast cells (CTMC) and mucosal mast cells (MMC) that may imply regional differences in the release of allergic mediators such as tumor necrosis factor-α (TNF-α) and eicosanoids.

Published in Mediators of Inflammation

ISSN: 0962-9351 (Print); 1466-1861 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Pathology
Website: https://onlinelibrary.wiley.com/journal/4792

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