ACS Omega
(Sep 2021)
Molecular Dynamics Simulations Identify Tractable Lead-like Phenyl-Piperazine Scaffolds as eIF4A1 ATP-competitive Inhibitors
- Derek J. Essegian,
- Tyler A. Cunningham,
- Christopher J. Zerio,
- Eli Chapman,
- Jonathan Schatz,
- Stephan C. Schürer
Affiliations
- Derek J. Essegian
- Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, United States
- Tyler A. Cunningham
- Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, United States
- Christopher J. Zerio
- Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, Tuscon, Arizona, United States
- Eli Chapman
- Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, Tuscon, Arizona, United States
- Jonathan Schatz
- Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, Florida, United States
- Stephan C. Schürer
- Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, United States
- DOI
-
https://doi.org/10.1021/acsomega.1c02805
- Journal volume & issue
-
Vol. 6,
no. 38
pp.
24432
– 24443
WeChat QR code
