Biological age and its role in stratification of cardiac risk

Abstract

Risk stratification in elderly patients is very important, as none of the applied models for the prediction of mortality in cardiac surgery does not take into account the whole complex of physiological features of the aging organism.The objective was to analyze the effectiveness of the method of qualitative assessment of biological age.Material and methods. Our study included 127 patients (87 male and 40 female) aged 65 to 84 years (mean age – 72.2±4.7 years) who underwent elective cardiac surgery. Perioperative factors were analyzed. The primary endpoint of the study was a 30-day mortality rate.Results. The total 30-day mortality rate was 13.4 % (17 patients). Perioperative predictors of 30-day mortality rate were the calculated values of the CAF scale (p=0.006), the surgery volume (p=0.044), the use of extracorporeal blood circulation (p=0.048).Conclusion. The use of qualitative assessment of biological age allows to more accurate predict the mortality in cardiac elderly patients.

Keywords

• cardiac surgery
• surgery
• aging
• frailty index