OsChz1 acts as a histone chaperone in modulating chromatin organization and genome function in rice

Kangxi Du; Qiang Luo; Liufan Yin; Jiabing Wu; Yuhao Liu; Jianhua Gan; Aiwu Dong; Wen-Hui Shen

doi:10.1038/s41467-020-19586-z

Nature Communications (Nov 2020)

OsChz1 acts as a histone chaperone in modulating chromatin organization and genome function in rice

Kangxi Du,
Qiang Luo,
Liufan Yin,
Jiabing Wu,
Yuhao Liu,
Jianhua Gan,
Aiwu Dong,
Wen-Hui Shen

Affiliations

Kangxi Du: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University
Qiang Luo: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University
Liufan Yin: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University
Jiabing Wu: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University
Yuhao Liu: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University
Jianhua Gan: Department of Physiology and Biophysics, School of Life Sciences, Fudan University
Aiwu Dong: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University
Wen-Hui Shen: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, International Associated Laboratory of CNRS-Fudan-HUNAU on Plant Epigenome Research, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University

DOI: https://doi.org/10.1038/s41467-020-19586-z
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 17

Abstract

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Function of CHZ-domain proteins in multicellular eukaryotes remains unclear. Here, the authors characterize the sole CHZ-domain protein identified in rice and show that it functions as an H2A/H2A.Z-H2B chaperone in dynamic regulation of chromatin organization and genome function.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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