PLoS ONE (Jun 2009)

Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam.

  • Heiman F L Wertheim,
  • Huyen Nguyen Nguyen,
  • Walter Taylor,
  • Trinh Thi Minh Lien,
  • Hoa Thi Ngo,
  • Thai Quoc Nguyen,
  • Bich Ngoc Thi Nguyen,
  • Ha Hong Nguyen,
  • Ha Minh Nguyen,
  • Cap Trung Nguyen,
  • Trinh Tuyet Dao,
  • Trung Vu Nguyen,
  • Annette Fox,
  • Jeremy Farrar,
  • Constance Schultsz,
  • Hien Duc Nguyen,
  • Kinh Van Nguyen,
  • Peter Horby

DOI
https://doi.org/10.1371/journal.pone.0005973
Journal volume & issue
Vol. 4, no. 6
p. e5973

Abstract

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Streptococcus suis can cause severe systemic infection in adults exposed to infected pigs or after consumption of undercooked pig products. S. suis is often misdiagnosed, due to lack of awareness and improper testing. Here we report the first fifty cases diagnosed with S. suis infection in northern Viet Nam.In 2007, diagnostics for S. suis were set up at a national hospital in Hanoi. That year there were 43 S. suis positive cerebrospinal fluid samples, of which S. suis could be cultured in 32 cases and 11 cases were only positive by PCR. Seven patients were blood culture positive for S. suis but CSF culture and PCR negative; making a total of 50 patients with laboratory confirmed S. suis infection in 2007. The number of S. suis cases peaked during the warmer months.S. suis was commonly diagnosed as a cause of bacterial meningitis in adults in northern Viet Nam. In countries where there is intense and widespread exposure of humans to pigs, S. suis can be an important human pathogen.