Иммуногистохимический и морфометрический анализ слизистой оболочки верхнечелюстной пазухи при выведении пломбировочных материалов в полость синуса

Abstract

By means of light microscopy, immunohistochemistry and morphometry it is established, that at odontogenic sinusitis caused by deducing root canal filling material, develop considerable changes in epithelial layer and stroma. In early terms (till 1 year) stay of root canal filling material in maxillary sinus in dominating processes in MM MS are an allergic inflammation with intensive infiltration of stroma by effectors cells, and epithelium reactions in a kind globet and bazalno-cellular hyperplasia. In stay terms of root canal filling material in sinus (till 5 years) in own plastic it is marked chronic cataral inflammation with high maintenance immunocompetent cells, dystrophies accompanied by the phenomena and desquamation of epithelial cells. At a long finding root canal material in maxillary sinus (more than 5 years) in MM develop sclerotic and atrophic changes, accompaning formation single-row epithelium. Despite high lymfocytes and plasma cells infiltration of stroma at odontogenic sinusitis caused by deducing root canal filling materials, parity CD4:CD8 in investigated groups below norm that testifies to infringements of local immunity MM MS.

Keywords

• верхнечелюстная пазуха
• одонтогенный синусит
• слизистая оболочка
• иммуногистохимия