Российский офтальмологический журнал (Oct 2018)
Pathogenesis of choked optic disc: mechanisms and consecutive stages of liquor and tissue edema of nerves
Abstract
The results of a 35-year long study of mechanism underlying the pathogenesis of the chocked optic disc under increased intracranial pressure are presented. The study is based on the theory of structural and functional histohematic regulating protective blood-ocular barrier. Different pressure levels of cerebrospinal fluid moving from the cranial cavity to the optic disc nerve were found to be regulated by histohematic and histocytic structures of the blood-ocular barrier. The obtained results validate the opinion that choked optic disc pathogenesis under increased intracranial pressure has a liquor tissue nature// Russian Ophthalmological Journal, 2017; 1: 63-8. doi: 10.21516/2072-0076-2017-10-1-63-68.
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