JACC: Case Reports (Apr 2023)

Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence

  • Akihisa Kataoka, MD, PhD,
  • Takahiko Shiba, DDS, PhD,
  • Sayaka Katagiri, DDS, PhD,
  • Shuhei Koyama, MD,
  • Kento Kito, MD,
  • Tatsuya Ota, MD,
  • Taiga Katayama, MD, PhD,
  • Yujin Ohsugi, DDS, PhD,
  • Takahiko Nagai, DDS,
  • Ryota Kobayashi, DDS,
  • Keiji Komatsu, DDS, PhD,
  • Masahiro Urata, MD,
  • Tomohiro Imazuru, MD, PhD,
  • Takanori Iwata, DDS, PhD,
  • Ken Kozuma, MD, PhD

Journal volume & issue
Vol. 11
p. 101793

Abstract

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We present 2 cases that both developed infective endocarditis and underwent mitral valve replacement. In addition to positive blood culture and echocardiographic findings, such as vegetation or mitral valve perforation, the 16S ribosomal RNA gene amplicon sequence approach used was helpful for disease diagnosis. (Level of Difficulty: Intermediate.)

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