JACC: Case Reports (Apr 2023)
Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence
- Akihisa Kataoka, MD, PhD,
- Takahiko Shiba, DDS, PhD,
- Sayaka Katagiri, DDS, PhD,
- Shuhei Koyama, MD,
- Kento Kito, MD,
- Tatsuya Ota, MD,
- Taiga Katayama, MD, PhD,
- Yujin Ohsugi, DDS, PhD,
- Takahiko Nagai, DDS,
- Ryota Kobayashi, DDS,
- Keiji Komatsu, DDS, PhD,
- Masahiro Urata, MD,
- Tomohiro Imazuru, MD, PhD,
- Takanori Iwata, DDS, PhD,
- Ken Kozuma, MD, PhD
Affiliations
- Akihisa Kataoka, MD, PhD
- Department of Medicine, Division of Cardiology, Teikyo University, Tokyo, Japan; Address for correspondence: Dr Akihisa Kataoka, Associate Professor, Department of Medicine, Division of Cardiology, Teikyo University, 2-11-1 Kaga, Itabashiku, Tokyo 173-8606, Japan.
- Takahiko Shiba, DDS, PhD
- Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan; Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA
- Sayaka Katagiri, DDS, PhD
- Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
- Shuhei Koyama, MD
- Department of Medicine, Division of Cardiology, Teikyo University, Tokyo, Japan
- Kento Kito, MD
- Department of Medicine, Division of Cardiology, Teikyo University, Tokyo, Japan
- Tatsuya Ota, MD
- Department of Medicine, Division of Cardiology, Teikyo University, Tokyo, Japan
- Taiga Katayama, MD, PhD
- Department of Medicine, Division of Cardiology, Teikyo University, Tokyo, Japan
- Yujin Ohsugi, DDS, PhD
- Department of Lifetime Oral Health Care Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
- Takahiko Nagai, DDS
- Department of Lifetime Oral Health Care Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
- Ryota Kobayashi, DDS
- Department of Lifetime Oral Health Care Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
- Keiji Komatsu, DDS, PhD
- Department of Lifetime Oral Health Care Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
- Masahiro Urata, MD
- Department of Cardiovascular Surgery, Teikyo University, Tokyo, Japan
- Tomohiro Imazuru, MD, PhD
- Department of Cardiovascular Surgery, Teikyo University, Tokyo, Japan
- Takanori Iwata, DDS, PhD
- Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
- Ken Kozuma, MD, PhD
- Department of Medicine, Division of Cardiology, Teikyo University, Tokyo, Japan
- Journal volume & issue
-
Vol. 11
p. 101793
Abstract
We present 2 cases that both developed infective endocarditis and underwent mitral valve replacement. In addition to positive blood culture and echocardiographic findings, such as vegetation or mitral valve perforation, the 16S ribosomal RNA gene amplicon sequence approach used was helpful for disease diagnosis. (Level of Difficulty: Intermediate.)
