Indian Journal of Endocrinology and Metabolism (Jan 2011)

Berardinelli Seip syndrome with insulin-resistant diabetes mellitus and stroke in an infant

  • C K Indumathi,
  • S Lewin,
  • Vageesh Ayyar

DOI
https://doi.org/10.4103/2230-8210.83054
Journal volume & issue
Vol. 15, no. 5
pp. 62 – 64

Abstract

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Berardinelli Seip congenital lipodystrophy (BSCL) is a rare metabolic disorder characterized by severe generalized lipodystrophy, insulin resistance, and dyslipedemia since infancy, and onset of overt diabetes mellitus in adolescence. Here we report a 5-month-old infant with clinical and metabolic manifestations of Berardinelli Seip syndrome including overt diabetes mellitus and stroke, which are very rare at this age.

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