Гинекология (Aug 2014)
Herbal medicines based on a black cohosh extract as a safe alternative for the correction of menopausal symptoms
Abstract
The review deals with the effectiveness and safety of plant hormones in the treatment of menopausal syndrome. Particular attention is given to black cohosh extract as a drug with distinction from other drugs in this group thanks to its action spectrum. The results of modern studies show that black cohosh extract is not so much phytohormonal as a natural vegetotropic agent that mediates its effect through serotonergic receptors. High-performance of black cohosh extract in relieving vasomotor symptoms is confirmed by comparative, placebo-controlled trials. However, no direct interaction with estrogen receptors defines security of black cohosh extract use. Long-term use of drugs based on black cohosh extract has no effect on the endometrium proliferative processes and mammary glands. Use of black cohosh extract can be considered a viable alternative to hormone replacement therapy in cases where it is impossible or undesirable.
