Is Irisin Anticancer Agent?

Abstract

Irisin is a protein, which is encoded by the FNDC5 gene. Irisin secreted as a hormone secret via Fibronectin type III domain-containing protein 5. Irisin is always provide beneficial effect of exercise on cellular metabolism as well as obesity and metabolic diseases. In addition, it plays a role in cancer. Therefore, in this study, aimed that to an overview of clinical research and explain the molecular mechanisms related to cancer of Irisin. This review will be providing a systematic analysis of recent work on Irisin and future work will provide a different perspective.

Keywords

• Irisin
• apoptosis
• molecular mechanism