PI3Kα inhibitor impairs AKT phosphorylation and synergizes with novel angiogenesis inhibitor AL3810 in human hepatocellular carcinoma

• Qin Xie,
• Shuaishuai Chi,
• Yanfen Fang,
• Yiming Sun,
• Linghua Meng,
• Jian Ding,
• Yi Chen

Affiliations

Qin Xie

College of Pharmaceutical Sciences, Zhejiang University

Shuaishuai Chi

Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Yanfen Fang

Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Yiming Sun

Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Linghua Meng

Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Jian Ding

Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Yi Chen

Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences