BioMedical Engineering OnLine (Feb 2020)

Epileptic seizure classifications using empirical mode decomposition and its derivative

  • Ozlem Karabiber Cura,
  • Sibel Kocaaslan Atli,
  • Hatice Sabiha Türe,
  • Aydin Akan

DOI
https://doi.org/10.1186/s12938-020-0754-y
Journal volume & issue
Vol. 19, no. 1
pp. 1 – 22

Abstract

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Abstract Background Epilepsy is one of the most common neurological disorders associated with disruption of brain activity. In the classification and detection of epileptic seizures, electroencephalography (EEG) measurements, which record the electrical activities of the brain, are frequently used. Empirical mode decomposition (EMD) and its derivative, ensemble EMD (EEMD) are recently developed methods used to decompose non-stationary and nonlinear signals such as EEG into a finite number of oscillations called intrinsic mode functions (IMFs). Our main objective in this study is to present a hybrid IMF selection method combining four different approaches (energy, correlation, power spectral distance, and statistical significance measures), and investigate the effect of selected IMFs extracted by EMD and EEMD on the classification. We have applied the proposed IMF selection approach on the classification of EEG signals recorded from epilepsy patients who are under treatment at our collaborator hospital. Multichannel EEG signals collected from epilepsy patients are decomposed into IMFs, and then IMF selection was performed. Finally, time- and spectral-domain, and nonlinear features are extracted and feature sets are created for the classification. Results The maximum classification accuracies obtained using various combinations of IMFs were 94.56%, 95.63%, 96.8%, and 96.25% for SVM, KNN, naive Bayes, and logistic regression classifiers, respectively, by using EMD analysis; whereas, the EEMD approach has provided maximum classification accuracies of 96.06%, 97%, 97%, and 96.25% for SVM, KNN, naive Bayes, and logistic regression, respectively. Classification performance with the same features obtained using direct EEG signals instead of the decomposed IMFs was worse than the aforementioned 2 approaches for every combination. Conclusion Simulation results demonstrate that the proposed IMF selection approach affects the classification results. Also, EEMD provides a robust method for feature extraction from EEG signals in order to classify pre-seizure and seizure segments.

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