Human miRNome profiling in colorectal cancer and liver metastasis development

Lisa Perilli; Silvia Pizzini; Andrea Bisognin; Susanna Mandruzzato; Marta Biasiolo; Arianna Facciolli; Elisabetta Rossi; Giovanni Esposito; Massimo Rugge; Pierluigi Pilati; Simone Mocellin; Donato Nitti; Stefania Bortoluzzi; Paola Zanovello

doi:10.1016/j.gdata.2014.06.017

Genomics Data (Dec 2014)

Human miRNome profiling in colorectal cancer and liver metastasis development

Lisa Perilli,
Silvia Pizzini,
Andrea Bisognin,
Susanna Mandruzzato,
Marta Biasiolo,
Arianna Facciolli,
Elisabetta Rossi,
Giovanni Esposito,
Massimo Rugge,
Pierluigi Pilati,
Simone Mocellin,
Donato Nitti,
Stefania Bortoluzzi,
Paola Zanovello

Affiliations

Lisa Perilli: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Silvia Pizzini: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Andrea Bisognin: Department of Biology, University of Padova, Padova, Italy
Susanna Mandruzzato: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Marta Biasiolo: Department of Biology, University of Padova, Padova, Italy
Arianna Facciolli: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Elisabetta Rossi: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Giovanni Esposito: Istituto Oncologico Veneto (IOV), IRCCS, Padova, Italy
Massimo Rugge: Surgical Pathology and Cytopathology Unit, Department of Medicine (DIMED), University of Padova, Padova, Italy
Pierluigi Pilati: Surgical Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Simone Mocellin: Surgical Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Donato Nitti: Surgical Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
Stefania Bortoluzzi: Department of Biology, University of Padova, Padova, Italy
Paola Zanovello: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy

DOI: https://doi.org/10.1016/j.gdata.2014.06.017
Journal volume & issue: Vol. 2, no. C
pp. 184 – 188

Abstract

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Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colorectal cancer has mainly been demonstrated in primary tumors. The miRNA expression profiles in 78 samples from 46 patients were analyzed to identify changes in miRNA expression level among normal colon mucosa, primary tumor and liver metastasis samples. Using this dataset, we describe the interplay of miRNA groups in regulating pathways that are important for tumor development. Here we describe in details the contents and quality controls for the miRNA expression and clinical data associated with the study published by Pizzini and colleagues in the BMC Genomics in 2013 (Pizzini et al., 2013). Data are deposited in GEO database as GSE35834 series.

Published in Genomics Data

ISSN: 2213-5960 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Biology (General): Genetics
Website: http://www.journals.elsevier.com/genomics-data/

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