Data on necrotic and apoptotic cell death in acute myocardial ischemia/reperfusion injury: the effects of CaMKII and angiotensin AT1 receptor inhibition
Tomas Rajtik,
Slavka Carnicka,
Adrian Szobi,
Zoltan Giricz,
Jin O-Uchi,
Veronika Hassova,
Pavel Svec,
Peter Ferdinandy,
Tanya Ravingerova,
Adriana Adameova
Affiliations
Tomas Rajtik
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic
Slavka Carnicka
Institute for Heart Research, Slovak Academy of Sciences & Centre of Excellence, SAS NOREG, Bratislava, Slovak Republic
Adrian Szobi
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic
Zoltan Giricz
Cardiometabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary
Jin O-Uchi
Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, USA
Veronika Hassova
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic
Pavel Svec
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic
Peter Ferdinandy
Cardiometabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary; PharmaHungary Group, Szeged, Hungary
Tanya Ravingerova
Institute for Heart Research, Slovak Academy of Sciences & Centre of Excellence, SAS NOREG, Bratislava, Slovak Republic
Adriana Adameova
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic; Correspondence to: Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Odbojarov 10, Bratislava 832 32, Slovak Republic. Tel.: +421 2 50117 366; fax: +421 2 50 117 100.
Content of particular proteins indicating cellular injury due to apoptosis and necrosis has been investigated in ischemic/reperfused (IR) hearts and ischemic/reperfused hearts treated with CaMKII inhibitor and/or AT1 receptor inhibitor. This data article provides information in support of the original research article “Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: a role of angiotensin AT1 receptor-NOX2 signaling axis” [1]. Keywords: Myocardial ischemia/reperfusion injury, CaMKII inhibition, AT1 receptor blockade, Apoptosis, Necrosis
